Towards a Better Model for the Microbe Membrane (Revisited)

Postdoc John Casey continues to work closely with MIT-CBIOMES Group PI Mick Follows on research combining quantitative proteomics, flux balance analysis, and molecular modeling of membrane transports to develop a steady-state model of microbial acclimation to substrate limitation. A paper by the same name was recently published in PLOS Computational Biology. Continue reading “Towards a Better Model for the Microbe Membrane (Revisited)”

Fellow Travelers

Observations suggest diazotrophs like Crocosphaera and Trichodesmium pay for their ability to fix nitrogen with a very low growth rate, yet diatom-diazotroph associations or DDAs exhibit high growth rates. CBIOMES postdoctoral fellow Chris Follett and co-authors use a cell flux model to test the hypothesis that diatom-diazotroph associations or DDAs grow faster than unpaired diazotrophs because the diatoms in DDAs provide organic carbon to their diazotroph guests that boost their growth rate. Continue reading “Fellow Travelers”