Towards a Better Model for the Microbe Membrane (Revisited)

Postdoc John Casey continues to work closely with MIT-CBIOMES Group PI Mick Follows on research combining quantitative proteomics, flux balance analysis, and molecular modeling of membrane transports to develop a steady-state model of microbial acclimation to substrate limitation. A paper by the same name was recently published in PLOS Computational Biology. Continue reading “Towards a Better Model for the Microbe Membrane (Revisited)”

Towards a Better Model for the Microbe Membrane

by John Casey for CBIOMES

CBIOMES Postdoctoral Fellow John Casey, has been working closely with MIT Group PI Mick Follows to combine quantitative proteomics, flux balance analysis of genome-scale metabolic models (GEMs), and molecular modeling in an attempt to estimate the parameters of a kinetic model based on transport fluxes, transporter abundances and structures, molecular diffusivity, and microscale fluid dynamics. Continue reading “Towards a Better Model for the Microbe Membrane”