Statistical Network Inference and
Time Series Analysis of Marine Ecosystems

Investigator: Jacob Bien, USC

Understanding ocean ecosystems critically hinges on our ability to uncover the complex relationships and interactions between living organisms and geochemical properties as they vary across space and time. As the scale and richness of marine data sets increase, the research questions being investigated become more ambitious and therefore more complicated to answer in a rigorous way. It becomes essential to address the methodological challenges associated with analyzing such datasets in a statistically sound and computationally efficient way.

In this project, we will develop statistical tools that can be used to infer the temporal and spatial interactions between large numbers of entities (e.g., microbial species) and the effect of other covariates (e.g. salinity and temperature) on these interactions. Recent developments from the high-dimensional statistics literature on graphical modeling and time series analysis will play a central role in this work. Efficient code will be produced and made publicly and freely available for marine researchers.

CBIOMES Collaborators in Bien’s Group

News from the Bien Group


Jann Paul Mattern, Kristof Glauninger, Gregory L. Britten, John R. Casey, Sangwon Hyun, Zhen Wu, E. Virginia Armbrust, Zaid Harchaoui, Francois Ribalet (2022), A Bayesian approach to modeling phytoplankton population...

February 2022 CBIOMES All Hands Poster Meeting

A big THANK-YOU to everyone who presented at the February e-meeting!  (more…)


Jacob Bien, Yan, X., Simpson, L., Christian L. Müller (2021), Tree-aggregated predictive modeling of microbiome data, Scientific Reports, doi: 10.1038/s41598-021-93645-3 Get the PDF [Requires login]  

Recordings and microtalks from the Bien Group. Please note access to this page is restricted to CBIOMES associates. (more…)

CBIOMES Welcomes Tim Coleman

A warm welcome to postdoc Tim Coleman who joins Jacob Bien's USC CBIOMES Group this month. (more…)

December 2020 CBIOMES (Poster) e-Meeting

To provide an opportunity to "pick up the conversation" and chat with colleagues about where work had gone since our Annual Meeting in June, the December gathering was an all-hands...

2020 Joint Simons Marine Collaborations Meeting

Please note access to this page is restricted to CBIOMES associates only. Besides CBIOMES, the Simons Foundation supports three other marine collaborations: BIOS-SCOPE, PriME, and SCOPE. A joint meeting, October...

The Bien Group goes to Annual Meeting

Jacob Bien's USC-CBIOMES group is using statistical network inference and time series analysis to bring together data and models. In this video, Jacob presents an overview of progress and current...

CBIOMES at CMStatistics2019

In December, several from CBIOMES traveled to London, England, to present their work at CMStatistics2019, a conference organized by the European Research Consortium for Informatics (ERCIM) Working Group on Computational...

CBIOMES Goes to Ocean Sciences 2020

Look out for members of the CBIOMES team, sharing their work at this year’s Ocean Sciences conference taking place February 16-21 in San Diego, California. (more…)

Recent Research in the Bien Group

Tackling the Statistical Challenges of Microbiome Data by Jacob Bien for CBIOMES Please note access to this news story is restricted to CBIOMES associates only. (more…)

CBIOMES Welcomes Sangwon (Justin) Hyun

A warm welcome to incoming postdoc Sangwon (Justin) Hyun in  Jacob Bien's USC CBIOMES Group. (more…)

Past Annual Reporting

2020 | 2019 | 2018 [login required]